Lead Sponsor

Saglik Bilimleri Universitesi

Age

6 - 12 years

Sex

ALL

Healthy Volunteers

Yes

•Pediatric patients between 6 to 12-year-old;
•Children must have a clinical history concordant to seasonal allergic rhinitis of the previous year;
•Children must have skin prick test (SPT) positivity to pollen (tree, grass, or weed) (Positive SPT is defined as; skin reaction with within 15 minutes after the test and 3 mm larger swelling compared to the negative control test; ALK, Hørsholm, Denmark)
•Children must have a total nasal symptom score (TNSS) of 4 or more on 4 of 7 days during the run-in period.

•Children who were treated with systemic/topical nasal corticosteroids, antihistamines or antibiotics, leukotriene receptor antagonists 4 weeks before the examination,
•those who had upper or lower respiratory tract infections;
•recipients of recent or ongoing allergen immunotherapy;
•active smokers;
•those with cystic fibrosis, immunodeficiency, septal deviation, nasal polyps, and ostio-metal complex, exudation, abnormal nasal diagnostic function, nasal anatomical disorder, metabolic disease, or congenital disease.
•Phone calls will measure children's adherence rate to treatment protocols, and participants determined to have treatment protocol adherence rates below 85% will be excluded.

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