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COMPLETEDNANCT04744233

Bioavailability of Carotenoids From Orange Juice in a Cross-over Study in Healthy Subjects.

Commercially available fruit juices are obtained after applying industrial technologies to preserve and extend the shelf-life by inactivation of microorganism and enzymes. These are traditional therma...

Lead sponsor: Instituto de Ciencia y Tecnología de Alimentos y Nutrición•2 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Instituto de Ciencia y Tecnología de Alimentos y Nutrición

Collaborators

Comunidad de Madrid
Instituto de Salud Carlos III
Puerta de Hierro University Hospital

Methods Twelve healthy subjects (6 men), age 20-32 y, were enrolled in a cross-over study, to consume 500 mL of orange juice/day during 14 days periods. All volunteers consumed the LP and HPP, six consumed PEF or FS-orange juice. Fasted blood was collected at baseline and on days 7 and 14. Carotenoid concentrations in serum and orange juice were analyzed by high performance liquid chromatogry (HPLC).

Age

20 - 32 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•age (20- 32 y)
•body mass index (BMI)
•serum cholesterol and triglycerides concentrations within the normal range
•serum retinol within the range 31 - 70 µg/dL.

Exclusion Criteria

•vitamin / mineral supplements intake
•regular medication
•pregnancy or lactating
•chronic disease
•smoking habit.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: February 9, 2021Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment12

Start dateOct 2001

Last updatedFeb 9, 2021

Condition

Biological Availability Carotenoids Lutein Humans

Locations shown

Madrid

Begoña Olmedilla-Alonso

Madrid

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 9, 2021Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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