Lead Sponsor

Nanjing University

Age

20 - 38 years

Sex

FEMALE

Healthy Volunteers

No

•1. The basal serum level of FSH was less than 10 IU / L
•2. Diagnosed with adenomyosis by ultrasound
•3. The first frozen thawed embryo transfer cycle, by hormone replacement protocol
•4. Transfer at least one high quality frozen embryo;
•5. Patients agreed to use low molecular weight heparin after FET, and they were able to sign informed consent in person.

•1. With abnormal karyotype;
•2. Accompanied with other uterine diseases: intrauterine adhesion, intramural myoma, moderate to severe endometriosis, congenital uterine malformation, endometrial tuberculosis, thin endometrium \< 8mm on the day of transformation, etc;
•3. PCOS, RIF patients;
•4. There are indications of conventional anticoagulation or antiplatelet therapy, such as antiphospholipid syndrome, autoimmune diseases, coagulation dysfunction, etc;
•5. There were contraindications to hormone replacement therapy and low molecular weight heparin;
•6. Participating in other clinical studies;
•7. Unable to follow-up