Contrast-Enhanced Ultrasound Scan for the Estimation of Tissue Pressure in Patients With Breast Cancer

Exclusion Criteria

• •Females who are pregnant or nursing
• •Patients who are medically unstable, patients who are seriously or terminally ill, and patients whose clinical course is unpredictable. For example:
• •Patients on life support or in a critical care unit
• •Patients with unstable occlusive disease (e.g., crescendo angina)
• •Patients with clinically unstable cardiac arrhythmias, such as recurrent ventricular tachycardia
• •Patients with uncontrolled congestive heart failure (New York Heart Association \[NYHA\] class IV)
• •Patients with recent cerebral hemorrhage
• •Patients who have undergone surgery within 24 hours prior to the study sonographic examination
• •Patients with known hypersensitivity or allergy to any component of Definity
• •Patients with unstable cardiopulmonary conditions or respiratory distress syndrome
• •Patients with uncontrollable emphysema, pulmonary vasculitis, pulmonary hypertension or a history of pulmonary emboli