Adipose Derived Mesenchymal Cell Treatment in Lungtransplantation

Exclusion Criteria

• •Recipients of multi-organ transplant, and or previously transplanted with any solid organ, including previous lung transplantation.
• •Patients scheduled for single lung transplantation.
• •Patients in need of acute transplantation e.g. patients on urgent call for transplantation and patients on respirator or on extra corporal membrane oxygenation (ECMO) treatment at time of transplantation.
• •Patients that based on crossmatch prior to transplantation have need for additional immunosuppressive treatment
• •Donor lung cold ischemic time \> 12 hours.
• •Patients with platelet count \< 50,000/mm3 at the evaluation before transplantation.
• •Patients who are unlikely to comply with the study requirements.
• •Patient unable to participate in the study for the full study period
• •Patients with any past (within the past 3-5 years) or present malignancy (other than excised basal cell carcinoma).
• •Females capable of becoming pregnant must have a negative pregnancy test prior to transplantation. After inclusion, they must use contraceptives for 2 months following the given stem cell treatment. The pill, spiral, depot injection of progesterone, sub-dermal implantation, hormonal vaginal ring and transdermal patch regarded as safe contraceptives.