diagnosis of Relapsing-Remitting (RR), Secondary Progressive (SP) and Primary Progressive (PP) MS;
age ≥ 18 and ≤ 75 years;
years of education ≥ 5;
no change of pharmacological treatment in the 6 months before the enrollment;
no clinical relapses or use of steroid treatment during 3 months before the enrollment;
provided informed consent for study participation.
You may not be if
history of nervous system disorders different from MS;
unstable psychiatric illness, such as psychosis or major depression;
severe disability with Expanded Disability Status Scale (EDSS) score \> 7.5;
severe cognitive impairment that would not enable PwMS to answer to questionnaires correctly (i.e. dementia), according to the patient's medical records.
