Efficacy and Mechanism of Action of Methenamine Hippurate (Hiprex™) in Women With Recurring Urinary Tract Infections.

Exclusion Criteria

• •1. Being on antibiotics at baseline (i.e. suppressive therapy or antibiotic therapy for urinary or non-urinary infections)
• •2. Neurogenic bladder condition
• •3. Using urinary catheters (including Foley catheter, intermittent catheterization, and suprapubic catheter)
• •4. Uncontrolled diabetes (HbA1c \> 9)
• •5. Chronic renal failure defined as serum creatinine \> 1.5 mg/dL
• •6. History of liver disease
• •7. Patients from out of town, in whom follow-up will not be possible
• •8. Pregnancy
• •9. Allergy to Hiprex
• •10. Inability to take Hiprex reliably at home, such as having psychosis, dementia, or swallowing disorders
• •11. Non-English speakers -