Given the significant unmet need for improved therapies that address migraine disorders and concurrent irritable bowel syndrome (IBS), this study seeks to investigate the impact of probiotics on the sequelae of symptoms associated with both migraine and IBS.
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Episodic migraine diagnosis for a minimum of 1 year (12-months)
Between 3-12 migraine episodes /month
Comorbid, symptomatic, irritable bowel syndrome during the screening period
On a steady treatment regimen: preventative and acute migraine medications and therapies unchanged over the last 6 months
Access to Scripps Center for Integrative Medicine
Access to smartphone or computer to complete electronic surveys
You may not be if
Other GI or hepatic diagnoses (Inflammatory Bowel Disease (IBD), Small Intestinal Bacterial Overgrowth (SIBO), Non-Alcoholic Fatty Liver Disease (NAFLD), elevated Liver Function Tests (LFTs) within the last 6 months)
Prior GI surgery
Prior GI infection in the previous 3-months
Antibiotic treatment in previous last 3 months
Diagnosed Autoimmune disease
Current corticosteroids use
Morbid obesity (BMI \>40)
Took Probiotics or Probiotic-containing supplements or therapy in the previous 3-months
Diagnosis of post-traumatic headache or cervicogenic headache
Pregnancy or plans to become pregnant during study participation
Clareo Health | Effects of a Multispecies Probiotic on Migraine