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Active Not RecruitingNANCT04684862

Infusion System for Hepatic Cancer

This is a single-site, open-label continued access study/treatment protocol under a treatment IDE. In addition to treating patients, the primary objective of this study is to assess the safety of usin...

Lead sponsor: Ronald DeMatteo, M.D.•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Ronald DeMatteo, M.D.

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Patients must be greater than or equal to 18 years of age
•Have a clinical or biopsy-proven diagnosis of colorectal cancer metastatic to liver or intrahepatic cholangiocarcinoma
•At the time of pump placement, patients will either have unresectable, chemotherapy-responsive disease or they will be undergoing resection with planned postoperative HAI
•Be deemed appropriate for pump chemotherapy by both a medical oncologist and a surgical oncologist
•Provision of signed and dated informed consent form

Exclusion Criteria

•Known active infection
•Is pregnant or breastfeeding or expecting to conceive children within the projected duration of the trial

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: December 15, 2025Terms

Trial snapshot

StatusACTIVE_NOT_RECRUITING

PhaseNA

Enrollment100

Start dateFeb 2021

Last updatedDec 15, 2025

Condition

Colorectal Cancer Metastatic to Liver Intrahepatic Cholangiocarcinoma

Locations shown

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: December 15, 2025Data synced to Clareo: May 17, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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