3. Laboratory testing: aspartate aminotransferase/platelet ratio index (APRI) \>2.0
4. CT, MRI or esophagogastroduodenoscopy (EGD) showing presence of esophageal varices
Patients with history of \> grade 2 HE within 180 days of enrollment based on review of clinical documentation verifying the event. If a description of HE symptoms is provided in clinical documentation, but it is unclear if it meets Grade 2 criteria, the principal investigator will assess the clinical documentation and provide an HE grade.
You may not be if
Non-English speaking
Model for End-Stage Liver Disease (MELD) Score \> 20
Pregnancy (self-reported)
Unable or unwilling to provide consent
History of liver transplant
Current or planned admission to a nursing facility
Serum creatinine \> 2.0 milligrams per deciliter (mg/dL) (with the exception that we will include patients with a serum creatinine \> 2.0 mg/dL if they are receiving hemodialysis)
Disorientation at the time of enrollment
Barcelona-Clinic Liver Cancer (BCLC) Stage D Hepatocellular Carcinoma with Child-Turcotte-Pugh (CTP) Class C