Microcephaly, Fanconi Anemia and Praxial Disorders

Our hypothesis is that children with FA present a developmental dyspraxia. This condition is very penalizing for children especially regarding graphic tasks, handwriting, whether or not they have skeletal malformations of the upper limbs. Consequences are fatigue because of energy expended trying to execute fine motor movements correctly. Main objective: To identify gesture dyspraxia in order to propose a targeted rehabilitation leading to national recommendations. Main Evaluation Criteria : 1. measurement of fine motor praxia 2. quantification of dyspraxia Secondary Objectives : To identify the musculoskeletal or tendinous anomalies in the upper limbs of AF children and to assess their functional consequences. To determine if these upper limbs abnormalities could influence the somatosensory map of this part of the body in the cerebral cortex. Secondary Evaluation Criteria : 1. MRI of the hand and forearm, orthopedic examination and functional assessment 2. Previously obtained brain MRI data