A Study of LY3484356 in Women With Breast Cancer Before Having Surgery

Exclusion Criteria

• •Have bilateral invasive breast cancer
• •Have metastatic breast cancer
• •Plan to receive concurrent neoadjuvant therapy with any other non-protocol anti-cancer therapy
• •Have had prior therapy (of any kind) for an invasive or non-invasive breast cancer
• •Have had prior radiotherapy to the ipsilateral chest wall for any malignancy
• •Have had prior anti-estrogen therapy with raloxifene, tamoxifen, aromatase inhibitor, or other selective estrogen receptor modulator (SERM), either for osteoporosis or prevention of breast cancer
• •Have had prior hormone-replacement therapy within 4 weeks of the start of study treatment
• •Have had major surgery within 28 days prior to randomization to allow for post-operative healing of the surgical wound and site(s)
• •Have certain infections such as hepatitis or tuberculosis or HIV that are not well controlled
• •Have another serious medical condition
• •Have a history of any other cancer (except nonmelanoma skin cancer or carcinoma in-situ of the cervix), unless in complete remission with no therapy for a minimum of 3 years