Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University Hospital, Grenoble
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Patient ≥18 years old
2. Suspicion of SARS CoV-2 infection based on clinical signs AND (positive PCR OR positive serology OR suggestive abnormalities on lung-imaging modalities)
3. Hospitalized patients with SpO2 ≤94% on room air requiring normobaric oxygen therapy with a nasal flow of O2 ≤ 6L / min to reach at least SaO2 ≥ 95%
4. Patient understanding and agreeing to comply with the planned study procedures
5. Patient affiliated with social security or beneficiary of such protection
6. Patient (or his legal representative) who has given his informed consent in writing before the start of any study procedure.
You may not be if
1. Pregnant or parturient women
2. Ratio of spontaneous blood ALT/AST\> 5 times the normal upper limit.
3. Stage 4 of severe chronic kidney disease or requiring dialysis (i.e. eGFR \<30)
4. Early transfer to another hospital within 72 hours.
5. Contraindication to any study drug, including a known allergy
6. Uncontrolled and clinically significant heart disease, such as arrhythmias, angina pectoris or uncompensated congestive heart failure
7. Patients treated in ambulatory care (i.e. not hospitalized)
8. Females of childbearing potential, defined as a premenopausal female capable of becoming pregnant, and not using an highly effective form of birth control.
9. Participant involved in another interventional clinical study
