Lead Sponsor

AlloVir

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Patients who had a kidney transplant performed greater than or equal to 28 days prior to enrollment
•At least 1 identified, suitably matched Posoleucel (ALVR105) cell line for infusion is available.
•Capable of giving signed informed consent which includes compliance with the requirements and restrictions listed in the informed consent form (ICF) and in the protocol.
•Contraceptive use by men and women should be consistent with local regulations regarding the methods of contraception for those participating in clinical studies.

•Undergone allogeneic hematopoietic cell transplantation
•Evidence or history of graft versus host disease (GVHD) or cytokine release syndrome (CRS).
•Uncontrolled or progressive bacterial or fungal infections
•Known or presumed pneumonia
•Ongoing therapy with high-dose systemic corticosteroids (ie, prednisone dose \>0.5 mg/kg/day or equivalent).
•Pregnant or lactating or planning to become pregnant.
•Weight \<40 kg.
•Patients who received, or planned to receive abatacept or belatacept, within 3 months of screening