HCV Epidemiological Survey in China Rural Area

Exclusion Criteria

• •Has history of decompensated liver diseases
• •Has been treated with other anti-virus drugs,or anti-tumor drugs,immuno-suppression drugs
• •Has a history of autoimmune hepatitis
• •History of a severe seizure disorder or current anticonvulsant use
• •History or other evidence of a medical condition associated with chronic liver disease other than HCV which would make the patient, in the opinion of the investigator, unsuitable for the study (e.g., hemochromatosis, autoimmune hepatitis, metabolic liver disease, alcoholic liver disease, toxin exposures)
• •Patients with documented or presumed coronary artery disease or cerebrovascular disease should not be enrolled if, in the judgment of the investigator, an acute decrease in hemoglobin by up to 4g/dL (as may be seen with ribavirin therapy) would not be well-tolerated
• •History of thyroid disease poorly controlled on prescribed medications, elevated thyroid stimulating hormone (TSH) concentrations with elevation of antibodies to thyroid peroxidase and any clinical manifestations of thyroid disease