Randomized Trial Investigating Melatonin Supplementation vs Placebo on Sleep Disturbance Following Total Joint Arthroplasty

Exclusion Criteria

• •1. Patients who undergo revision total joint arthroplasty
• •2. Patients who undergo bilateral total joint arthroplasty
• •3. Patients currently taking melatonin supplementation
• •4. Patient has history of substance abuse (drug or alcohol)
• •5. Patient is a workman's comp patient or patient has current litigation pending
• •6. Patient has an allergy to melatonin
• •7. Patient has a history of delirium/psychiatric/depression/on antidepressants
• •8. Patient has a history of insomnia/ on sleep aid medication
• •9. Anyone on warfarin
• •10. Sleep apnea
• •11. Patient discharged to SNF or rehab
• •12. Patients who have inflammatory conditions
• •13. Shift work or night work