Diagnostic criteria. Current diagnosis of AN, including being underweight below 17.5 body mass index (BMI, kg/m2), will have a severe fear of weight gain, body image distortion and absence of the menstrual cycle over three consecutive months (if applicable).
First 1-2 weeks in treatment at The University of California San Diego Eating Disorders Center for Treatment and Research or Rady Children's Hospital San Diego Medical Behavioral Unit.
Restricting subtype, that is without binge/purge behaviors
Current pregnancy or breast feeding within last 3 months
Illiterate/Blind individuals
First degree relative with current or past eating disorder
Current Medications other than BCP or IUD
Past or present Axis I psychiatric disorder including substance or alcohol use disorder as determined through PI interview and MINI-Kid clinical interview
Major Medical illness (as determined through medical history in bioscreen and PI interview) such as:
* Conditions that are life threatening:
* cancer
* heart disease
* stroke
* HIV/AIDS
* Seizure Disorders
* Conditions that are life threatening Conditions that cause serious disability without necessarily being life threatening:
* stroke
* closed head or spinal cord injuries
* mental retardation
* congenital malformations.
* Conditions that cause significant pain or discomfort that can cause serious interruptions to life activities:
* severe allergies
* migraine
* arthritis
* sickle cell disease
* Conditions that require major commitments of time and effort from care-givers for a substantial period of time:
* mobility disorders
* blindness
* Alzheimer's disease and other dementias
* chronic obstructive pulmonary disease
* paraplegia or quadriplegia
* Down's syndrome
* depression
* Conditions that may require frequent monitoring:
* diabetes
* conditions requiring anticoagulation treatment
* severe asthma
* severe allergies
* schizophrenia and other psychotic illnesses.
* Conditions that predict or are associated with severe consequences:
* hypertension (associated with heart disease)
* depression (associated with suicide)
* diabetes (associated with blindness, kidney failure)
* alcohol and other substance abuse (associated with intentional and unintentional injuries).
Recent history of suspected substance abuse or a lifetime history of psychostimulant abuse and/or dependence
Metal implants or braces (as determined through fMRI screening form)
Anorexia Nervosa
Pregnancy or breast feeding within last 3 months
Lifetime history of bipolar disorder or psychosis
Illiterate/Blind individuals
Use of an anti-psychotic or other dopamine acting medication including stimulants within the past week at time of MRI
Recent history of substance abuse or dependence (within the last month)
Major Medical illness (as determined through medical history in bioscreen and PI interview) such as:
* Conditions that are life threatening:
* cancer
* heart disease
* stroke
* HIV/AIDS
* Seizure Disorders
* Conditions that are life threatening Conditions that cause serious disability without necessarily being life threatening:
* stroke
* closed head or spinal cord injuries
* mental retardation
* congenital malformations.
* Conditions that cause significant pain or discomfort that can cause serious interruptions to life activities:
* severe allergies
* migraine
* arthritis
* sickle cell disease
* Conditions that require major commitments of time and effort from care-givers for a substantial period of time:
* mobility disorders
* blindness
* Alzheimer's disease and other dementias
* chronic obstructive pulmonary disease
* paraplegia or quadriplegia
* Down's syndrome
* Conditions that may require frequent monitoring:
* diabetes
* conditions requiring anticoagulation treatment
* severe asthma
* severe allergies
* schizophrenia and other psychotic illnesses.
* Conditions that predict or are associated with severe consequences:
* hypertension (associated with heart disease)
* diabetes (associated with blindness, kidney failure)
* alcohol and other substance abuse (associated with intentional and unintentional injuries) within the last month
Metal implants or braces (as determined through fMRI screening form)
