Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Pennsylvania
Age
16–40
Sex
FEMALE
Healthy volunteers
Accepted
You may be eligible if
Female sex assigned at birth
Age 16-40 years old
Acne defined as at least 10 inflammatory papules or pustules and an Investigator's Global Assessment (IGA) score of at least 2 as measured by the Comprehensive Acne Severity Scale
Not currently pregnant or planning to become pregnant
You may not be if
Pregnancy
Heart disease
Renal disease
Liver disease
Orthostatic hypotension
Addison's disease
History of hyperkalemia
Allergy to tetracycline-class antibiotic
Allergy to spironolactone
Concomitant use of medications known to interact with spironolactone or doxycycline or that may increase the risk for hyperkalemia, including angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, eplerenone, nonsteroidal anti-inflammatory drugs, and digoxin.
Treatment with spironolactone, an oral antibiotic, laser, photodynamic therapy, or chemical peel within the past 4 weeks
Treatment with isotretinoin within the past 3 months
