Dose-Response Study of MR-107A-01 in The Treatment of Post-Surgical Dental Pain

Exclusion Criteria

• •1. Previously dosed with MR-107A-01.
• •2. Subject with known hypersensitivity to nonsteroidal antiinflammatory drugs (NSAIDs).
• •3. Active GI bleeding or a history of peptic ulcer disease, active inflammatory bowel disease, e.g., Crohn's Disease or ulcerative colitis, bleeding disorders that may affect coagulation.
• •4. Use of any investigational drug within 28 days, or 5 half-lives, prior to screening whichever is longer.
• •5. Use of medications with the potential to interact with MR-107A-01.
• •6. Other acute or chronic medical or psychiatric condition or laboratory abnormality that may increase the risk associated with study participation or investigational product administration or may interfere with the interpretation of study results and, in the judgment of the investigator, would make the subject inappropriate for entry into this study.