Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Kessler Foundation
With
St. Barnabas Medical Center
The researchers aim is to investigate the effects of Tysabri on cognitive fatigue and on specific brain areas that have been shown to underlie cognitive fatigue in individuals with RRMS. The researchers will investigate the effects on the cognitive fatigue that develops during the performance of a demanding task and also on how cognitive fatigue changes as a function of duration of treatment.
Age
18–64
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Age between 18-64
Diagnosed with Relapsing-Remitting Multiple Sclerosis or a healthy volunteer
If diagnosed with MS: has been newly prescribed Tysabri, but has not yet started taking the medication
Can read and speak English fluently
You may not be if
History of head injury, stroke, seizures, or any other significant neurological event other than MS
Flare up of MS symptoms within the past month
History of significant psychiatric illness (for example, bipolar disorder, schizophrenia, or psychosis) or a current diagnosis of Major Depressive Disorder
Pacemaker or other implanted electrical device, brain stimulator, aneurysm clip (metal clips on the wall of a large artery), metallic prostheses (including metal pins and rods, heart valves, and internal hearing aids \[cochlear implants\]), permanent eyeliner, implanted delivery pumps, or shrapnel fragments
Left-handed.
Not able to have an MRI
Clareo Health | Examining Effects of Tysabri on Cognitive Fatigue Using fMRI
