Effect of Magnesium Sulphate Added to Mepivacaine Hydrochloride on Inferior Alveolar Nerve Block Success in Patients With Symptomatic Irreversible Pulpitis in Mandibular Molars: A Randomized Clinical Trial.

Exclusion Criteria

• •1. Patients who had used any type of analgesic medication during the preceding 12 hours before the treatment.
• •2. Pregnant or nursing females.
• •3. Patients having significant systemic disorder (ASA III or IV).
• •4. Drug abusers and subjects who were on antidepressant medication.
• •5. Re-treatment cases.
• •6. Patients with a contraindication for the use of magnesium sulphate or those known to be allergic to any of the study medications.