Cardiac Magnetic Resonance Guidance of Implantable Cardioverter Defibrillator Implantation in Non-ischemic Dilated Cardiomyopathy

Exclusion Criteria

• •ICM \[previous myocardial infarction, previous percutaneous coronary intervention\]
• •Other cardiomyopathies (hypertrophic cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy, restrictive cardiomyopathy, infiltrative cardiomyopathies \[e.g. cardiac amyloidosis, cardiac sarcoidosis, hemochromatosis and iron overload cardiomyopathy\], left ventricular non-compaction cardiomyopathy, reversible cardiomyopathies \[Takotsubo syndrrome, peripartum cardiomyopathy, chemotherapy induced cardiomyopathy\].
• •Myocarditis
• •Contraindication for CMR at study entry (including severe claustrophobia, pacemaker or ICD, metallic cerebral or intracranial implants, known allergy to gadolinium)
• •Severe renal insufficiency (creatinine clearance \<30 mL/min)
• •Current pacemaker or defibrillator in situ
• •Current indication for device therapy (e.g. secondary prophylaxis after aborted SCD)
• •Renal impairment defined as an eGFR \<30 milliliters
• •Age \<18 years
• •Patients presenting with pregnancy
• •Patients without informed consent
• •Participation in another randomized trial
• •Life expectancy \<2 years