1. Contraindication to MRI

2. Pregnancy

3. Lactation

4. Individuals who are unable to participate in the imaging portion due to severity of their medical condition

5. Chronic infectious disease (e.g. HIV, HCV)

6. Chronic inflammatory disease (e.g., fibromyalgia, MS, etc) or autoimmune disease

7. Viral or bacterial illness requiring medical attention and/or antibiotics within 1 month of study participation

8. Blood or blood clotting disorder

9. Cancer that has metastasized to the brain

10. Positive urine hCG test day of procedure or a serum hCG test within 48 hours prior to the administration of \[18F\]DPA-714 and \[11C\]PiB.

11. Currently enrolled in a clinical trial utilizing experimental therapies.

12. Low affinity binder for TSPO ligands based on genotyping for SNP rs6971.

13. Prior brain tumor or other neurological condition known to affect cognition

14. A diagnosis of dementia unrelated to cancer or an adjusted MMSE score \< 24

Neuroinflammation and Age-associated Brain Pathology: Two Potential Mechanisms of Cognitive Impairment in Ovarian Cancer