Liposomal Bupivacaine in Adductor Canal Blocks (ACB)

Exclusion Criteria

• •1. Patients unwilling or unable to consent to participate in the study.
• •2. Prisoners.
• •3. Pregnancy.
• •4. Reported to have mental illness or belonging to a vulnerable population.
• •5. Subject is \< 18 years of age.
• •6. Patients receiving general anesthesia for the total knee arthroplasty.
• •7. Subject has impaired decision-making capacity per discretion of the Investigator.
• •8. Any condition for which the primary anesthesia care team deems neuraxial anesthesia inappropriate.
• •9. Significant pre-existing neuropathy on the operative limb.
• •10. Significant chronic pain disorders (i.e. fibromyalgia, complex regional pain syndrome I \& II, among others).
• •11. Subject has sustained a significant trauma to the operative knee.
• •12. Chronic Opioid Use (daily or almost daily use of opioids for \> 3 months).
• •13. Known hypersensitivity and/or allergies to local anesthetics.
• •14. Previous surgery on the affected knee excluding arthroscopic or open meniscectomy.
• •15. Patients with impaired renal function such that they cannot receive IV Toradol.