During admittance due to acute exacerbation of chronic obstructive lung disease will patience have an echocardiography to examine their pulmonary pressure. If patient have a tricuspidal return gradient above 40 mmHg, they will receive treatment with a phosphordiesterase-5-inhibitor, Sildenafil.
Age
40–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
COPD verified by specialist and spirometry
Admitted with the diagnosis "acute exacerbation of COPD"
TR-gradient ≥40 mmHg verified by specialist and echocardiography
Informed consent
You may not be if
Known pulmonal hypertension
Known heart disease which affects the pump function of the heart
Men \<40 years
Women \<55 years
Not-menopauseal women \<55 years (Menopause is defined as no menstruation within 12 months.)
Severe mental illness which significantly complicates cooperation
Severe language difficulties which significantly complicates cooperation
known allergy to Sildenafil
Sildenafil consumption ≥50 mg / week due to other indications
