Time between symptom onset and inclusion ≤ 7 days;
Chest tomography with \<50% involvement of the lung parenchyma;
No indication of ventilatory support at the time of randomization;
Sign the consent form.
Convalescent plasma donation will be eligible for patients ≥ 18 years old who had previously confirmed COVID-19 by RT-PCR, which met the criteria adopted by technical notes n13 and 21/2020-CGSH/DAET/SAES/MS;
SARS-COV-2 negative RT-PCR;
Asymptomatic for at least 14 days;
SARS-CoV-2 anti-peak titre with dilution ≥ 1: 320;
Sign the consent form.
You may not be if
Contraindication to transfusion or history of previous reactions to blood products for transfusion;
Pregnant women;
Limiting comorbidity for administering the therapies provided for in this protocol in the opinion of the investigator.
Female gender with previous pregnancy;
Absence of peripheral venous network compatible with the apheresis procedure;
Positive or indeterminate result in any of the infectious screening tests;
Presence of intellectual incapacity to understand the guidelines regarding the risks and benefits of participating in the study.
Clareo Health | Convalescent Plasma for Treating Patients With COVID-19 Pneumonia Without Indication of Ventilatory Support
