Assessment of 99mTc-NTP 15-5 Uptake on Cartilage, a New Proteoglycan Tracer

Exclusion Criteria

• •Patients \<18 years of age.
• •Pregnant or lactating patient.
• •BMI\> 30
• •History of known allergy to excipients contained in the solution of 99mTc-NTP 15-5
• •Chronic inflammatory rheumatism (rheumatoid arthritis, spondyloarthropathy, psoriatic arthritis, etc.) diffuse arthritis (at least 3 joints affected), autoimmune connectivitis, fibromyalgia.
• •Known chronic joint pathology: osteoarthritis affecting at least 3 joints, autoimmune disease, inflammatory rheumatism (except unilateral knee arthritis).
• •Persons deprived of their liberty, under guardianship / curatorship, or safeguard of justice.
• •Treatment with NSAIDs or cessation of less than 48 h.
• •Inability to comply with medical requirement / follow-up of the trial for geographic, family, social or psychological reasons. These conditions should be discussed with the patient before registration in the study.