Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
AstraZeneca
Age
20–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Outpatients aged ≥20 years
Hyperkalemia patients defined as meeting either of the following criteria:
1. Having a history of S-K ≥5.1 mmol/L ≥2 times within 6 months before enrolment
2. Having a history of S-K ≥5.5 mmol/L once within 6 months before enrolment
3. Currently treated by potassium binders for the treatment of hyperkalemia at enrolment
Having been diagnosed as CKD (≥stage 3b) or HFrEF by investigators as defined below:
CKD is diagnosed based on the guidelines of CKD issued by the Japanese Society of Nephrology (JSN, 2018) as being either or both of condition 1 and 2 for ≥3 months
1. Clear sign of kidney impairment based on urinalysis, imaging, blood test, or biopsy. Especially, existence of ≥0.15 g/gCr of proteinuria (≥30 mg/gCr of albuminuria) is important.
2. GFR \<45 mL/min/1.73m2 Within the routine clinical practice, GFR is estimated by serum creatinine, gender, and age using following the formulation.
eGFR creat (mL/min/1.73m2) = 194 x serum creatinine (mg/dL)-1.094 x age (years)-0.287 (for female patients, x 0.739)
≥Stage 3b CKD is diagnosed based on the following eGFR categories:
