Geniculate Artery Embolization for Osteoarthritis

Exclusion Criteria

• •BMI \>35 kg/m2
• •Advanced peripheral arterial disease (resting ABI \<= 0.9).
• •Known significant peripheral arterial disease precluding common femoral catheterization
• •Have smoked tobacco regularly (smoking 1 or more tobacco product(s) per week) within the last year
• •Diabetics with hemoglobin A1C of \>9%
• •Previous lower extremity embolization
• •Uncontrolled emotional disorders per patient medical history
• •Chronic pain syndrome or currently under a pain contract.
• •Anatomic variants involving the lower extremities which would increase the risk of non-target embolization
• •Renal insufficiency based on an estimated GFR\<45 ml/min who are not already on hemodialysis.
• •Abnormal INR (\>1.5)
• •Platelet count \<50x109/L.
• •Currently receiving medications for anticoagulation which cannot safely be held for the procedure and for 7 days post-procedure.
• •Known severe allergy to iodine which cannot be adequately pre-medicated
• •Pregnant or intend to become pregnant within 6 months of the procedure
• •Contraindication to drugs used for moderate sedation during interventional procedures, including Midazolam and Fentanyl
• •Life expectancy \<60 months
• •Currently enrolled or who plan to enroll in other investigations that conflict with follow-up testing or confounds data in this trial
• •Contraindications to medical and physical rehabilitative treatments of OA.
• •Advanced atherosclerosis.
• •Current or previous lower extremity fistula.
• •Rheumatoid arthritis or seronegative arthropathies.
• •WOMAC Pain Scale \< 6
• •Steroid injection in the affected joint within 3 months of screening. I- n investigator assessment, patient is not a candidate for study participation