Enhancing Ultrasound & Photoacoustic for Recognition of Intestinal Abnormalities

Exclusion Criteria

• •1. Stoma independent of localization, ileoanal pouch
• •2. Prior bowel surgery other than ileocecal resection, which potentially affects the study procedure by fundamentally changing bowel anatomy by removing the ROI (e.g. (partial) resection of the sigmoid, left sided colon) or repositioning the ROI to an inaccessible location (e.g. right-sided colectomy with transversostomy)
• •3. Indeterminate Colitis, irritable bowel syndrome (IBS)
• •4. Involvement of the upper gastrointestinal (GI) track only
• •5. Isolated proctitis
• •6. Complications, such as infectious enteritis, infectious colitis and infectious enterocolitis, abscess formation, intestinal obstruction, toxic megacolon
• •7. Tattoo in skin area of interest
• •8. Skin lesions, scar tissue or skin diseases affecting the area of imaging
• •9. Highly pigmented skin in the area of imaging (e.g. Fitzpatrick skin type V and VI)
• •10. The bowel wall is invisible in the Ultrasound image of the MSOT system
• •11. Medication leading to increased light sensitivity
• •12. Pregnant and breastfeeding women
• •13. Mental retardation of the patient with restriction of general judgment and awareness
• •14. Exclusion due to safety concerns of investigator (subject who has any condition, including any physical, psychological, or psychiatric condition, which in the opinion of the Investigator, would compromise the safety of the subject or the quality of the data and renders the subject an unsuitable candidate for the study)