Algorithm Using LINQ Sensors for Evaluation And Treatment of Heart Failure

Exclusion Criteria

• •Patient is currently implanted with a cardiovascular implantable electronic device (CIED) (e.g. ICM, pacemaker, ICD, CRT-D or CRT-P device) or hemodynamic monitor.
• •Patient is receiving temporary or permanent mechanical circulatory support.
• •Patient had MI or PCI/CABG within past 90 days.
• •Patient has had a heart transplant, or is currently on heart transplant list.
• •Patient has severe valve stenosis on echocardiogram.
• •Patient has primary pulmonary hypertension (pre-capillary, WHO group 1,3,4,5).
• •Patient is on chronic intravenous inotropic drug therapy (e.g. dobutamine, milrinone).
• •Patient has severe renal impairment (eGFR \<30 mL/min).
• •Patient has systolic blood pressure of \< 90 mmHg at the time of enrollment.
• •Patient is on chronic renal dialysis.
• •Patient is unable to undergo one round of PRN medication intervention (i.e. 4 days of increased diuretics dose).
• •Patient has liver disease, defined as AST/ALT \>5x normal, or bilirubin \>2x normal.
• •Patient has serum albumin \< 3 g/dL.
• •Patient has hypertrophic obstructive cardiomyopathy, constrictive pericarditis or amyloidosis.
• •Patient has complex adult congenital heart disease.
• •Patient has active cancer involving chemotherapy and/or radiation therapy.
• •Patient weighs more than 500 pounds.
• •Patient is pregnant or breastfeeding (all females of child-bearing potential must have a negative pregnancy test within 1 week of enrollment).
• •Patient is enrolled in another interventional study.