Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University Hospital Muenster
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Signed informed consent form
Diagnosis of relapsing-remitting multiple sclerosis according to 2017 revised McDonald-criteria
Incomplete remission of relapse symptoms following initiation treatment with 1000mg/d intravenous methyl prednisolone
Absence of fever or clinically apparent signs of infection
You may not be if
Baseline EDSS score \>6.5 points
Previous administration of less than 3x1000mg or more than 5x1000mg IVMPS for initiation treatment
Known pregnancy or rejection to perform a pregnancy test (female patients only)
Immunosuppressive treatment for conditions other than multiple sclerosis
Ongoing neoplastic disorder or past neoplastic disorder within previous five years
Known or newly diagnosed HIV-, HBV- or HCV-infection
Regular intake of ACE inhibitor drugs
Known bleeding disorders (including laboratory abnormalities such as: (I) platelet count\<50.000/µL; (II) international normalized ratio\>1.5, (III) activated prothrombin time\>50s) or intake of oral anticoagulant drugs
Clareo Health | Immunoadsorption Versus High-dose Intravenous Corticosteroids in Relapsing Multiple Sclerosis