Objectives:
1. To identify Measles IgG titre in SARS-COV2 infected patients .
2. correlate level of Measles IgG titre with the clinical severity of COVID-19 disease.
Secondary Objective To find an association of the postulated protective role of measles vaccine and SARS-COV2 infection
Criteria:
Inclusion criteria:included patients would be divided into 3 groups according to clinical severity of COVID-19 disease (mild ,moderate \& severe)
* All patients with confirmed COVID 19 confirmed by positive PCR . .
* Any age or gender.
Exclusion criteria:
\- Any patient refusing to be involved in the study.
Methods:
* Informed consent will be taken from each subject
* Full clinical examination.
* Evaluation of Measles Antibody Titer:
The measles virus IgG antibody titer will be determined quantitatively by ELISA for quantitative determination of IgG class antibodies against Measles virus in human serum or plasma (citrate, heparin).
\- Anonymous data will be retrieved from the admitted patients' files, such as:
* CBC, CRP, AST, ALT, ESR, Serum ferritin \& SARS CoV 2 RNA PCR swab results.
* Chest X ray and/or CT chest.
