Safety and Efficacy of HST 001 in Male Pattern Hair Loss

Exclusion Criteria

• •1. History of keloid formation or significant hyperpigmentation
• •2. History of other forms of hair loss - Alopecia areata, trichotillomania, scarring alopecia etc.
• •3. History of acute or chronic illness that in the opinion of the investigator might confound the results of the study including some drug medications
• •4. Active skin diseases (eczema, atopic dermatitis, psoriasis, skin cancer, sun-damaged skin with actinic keratosis on the scalp, etc.) in or around the area to be treated
• •5. Routine use of prescription anti inflammatory medications, immunosuppressive drugs, or antihistamine medications
• •6. Use of topical drugs or other cosmetics on the scalp
• •7. Use of over the counter (OTC) or prescriptive topical hair treatments, including hair transplantation during the last 6 months
• •8. Currently using a hair system or wig
• •9. History of hair transplants or scalp reduction surgery
• •10. History of allergy or intolerance to lidocaine and/or epinephrine
• •11. Use of hair dye within 3 days of the treatments, otherwise, willing to maintain the same hair color for the study duration
• •12. Current enrollment in an investigational drug or device study
• •13. Has tattoos or scars in scalp that would interfere with visual assessment
• •14. Is an employee of the investigator's site, and employee or representative of Histogen, investor, or a relative with one of the above
• •15. Has a condition or is in a situation which, in the investigator's opinion, may put the participant at significant risk, may confound the study results, or may interfere significantly with participant's involvement in the study
• •16. Known allergy to rice
• •17. Known allergy to bovine products