Lead Sponsor

Naval Hospital, Athens

Collaborators

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•chief complaint of at least one of the following symptoms: dryness, foreign-body sensation, burning, and tearing for 3 months
•diagnosis of DED secondary to MGD with eyelid margin telangiectasias in both eyes
•a baseline Ocular Surface Disease Index (OSDI) score ≥ 40
•tear break-up time (TBUT) ≤ 5 seconds
•corneal fluorescein staining ≥ 6 as per the National Eye Institute (NEI) grading scale for corneal staining.

•history of ocular trauma or surgery
•use of any treatment for DED or MGD other than artificial tears within the past 3 months
•active allergy, infection, or inflammatory disease at the ocular surface unrelated to DED or MGD
•lacrimal drainage system anomalies
•contact lens wear
•use of any systemic or topical anti-inflammatory medicine