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Effects of Platelet Rich Plasma on Endometrium | Clinical Trials | Clareo Health

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COMPLETEDNANCT04424160

Effects of Platelet Rich Plasma on Endometrium

Intrauterine platelet rich plasma will be injected in the endometrial region via the vaginal route after the cessation of menstrual period. The endometrial thickness will be assessed under ultrasound ...

Lead sponsor: Acibadem University•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Acibadem University

Collaborators

Baskent University

Intrauterine platelet rich plasma will be injected in the endometrial region via the vaginal route after the cessation of menstrual period. In the second menstrual period following the PRP injection, the endometrial thickness will be assessed under ultrasound and hormone replacement will be started. As the endometrial thickness reaches adequate thickness during ultrasound follow-up, embryo transfer will be performed. Pregnancy test results will be recorded and followed.

Age

20 - 45 years

Sex

FEMALE

Healthy Volunteers

No

Inclusion Criteria

•Women in whom cycle was cancelled due to an endometrial thickness \<7 mm when progesterone start was planned in patients undergoing frozen embryo transfer with hormone replacement therapy
•Women with a history of Asherman syndrome, but no obvious intrauterine adhesion in the last hysteroscopic procedure;
•Women who have at least 2 frozen good-quality embryos.

Exclusion Criteria

•Women with any other known cause of implantation failure, such as poor embryo quality, or congenital uterine anomalies, endometrial polyp or fibroid,
•Previous diagnosis of any malignancy,
•Anticoagulant use for which plasma infusion is contraindicated,

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: April 20, 2021Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment150

Start dateSep 2020

Last updatedApr 20, 2021

Condition

Asherman Syndrome

Locations shown

Acıbadem Maslak Hospital IVF Unit

Istanbul

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 20, 2021Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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