Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Piero Luigi Ruggenenti
With
Aferetica
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Plasma Ig Donors
Adult (\>18 and \<65-yr-old) men and women
Convalescent donor who recovered from COVID 19 from at least 14 days according to the clinical and laboratory criteria defined by the Consiglio Superiore di Sanità on February 20, 2019 ("The recovered patient is the one who resolves the symptoms of COVID-19 infection and who is negative in two consecutive tests for the search for SARS-Cov-2, performed 24 hours apart") with the exceptions mentioned in the attached derogation (that is "no upper age limit to donation provided there are no clinical contraindications to the procedure and independent of documented evidence of two negative tests for SARS-Cov 2 naso-faringeal contamination")
Male or female donor; if female only if nulliparous; in both cases with a negative history of blood component transfusions
Careful clinical evaluation of the patient-donor with particular reference to the criteria established by current legislation to protect the health of the donor who donates by apheresis
Presence of adequate levels of neutralizing anti-SARS-COV-2 antibodies;
Biological qualification test negative defined by current indications (performed at SIMT of HPG23)
Test negative for: HAV RNA, HEV RNA, PVB19 DNA (performed at HPG23)
Informed written consent
Recipients
\>18 years of age
COVID-19 pneumonia diagnosed by standard criteria (viral detection in naso-faringeal or bronco-alveolar lavage by RT-PCR for SARS-COV-2, typical Chest X Ray or CT Scan, ventilatory dysfunction not directly explained by heart failure or fluid overload)
Respiratory failure (i.e. room air PaO2\<60 mmHg) needing oxygen support with Venturi mask (FiO2 between 28 and 60%), non-rebreathing mask or high flow-nasal cannula (HFNC);
Patient written informed consent
You may not be if
Need of Continuous Positive Airway Pressure (CPAP) ventilator support, Non-Invasive Ventilation (NIV) or intubation for invasive mechanical ventilation
Involvement in any clinical trial
Clareo Health | Convalescent Antibodies Infusion in COVID 19 Patients
