Patients with pneumonia or severe illness requiring admission to ICU.

Severe chronic kidney disease (i.e. estimated glomerular filtration rate (eGFR) \< 30) or end stage renal disease requiring dialysis

Sever chronic liver disease (Alanine transaminase/aspartate transaminase (ALT/AST) \> 5 times the upper limit of normal).

Pregnancy or breast feeding.

Anticipated transfer to another hospital which is not a study site within 72 hours.

Allergy to any study medication.

Nigella Sativa in COVID-19