EASiVENT Study Comparing INTELLiVENT-ASV vs Non Automated Ventilation in Adult ICU Patients

Exclusion Criteria

• •Fulfilling weaning criteria according to the weaning procedure of the ICU
• •Need for "rescue therapy" (e.g: ECMO)
• •Brain death status
• •Respiratory drive disorder (Cheyne-Stokes breathing)
• •Arterial hypoxia due to a non-pulmonary condition (right-to-left shunting due to congenital disease, hepato-pulmonary syndrome, )
• •Broncho-pleural fistula
• •Chronic or acute dyshemoglobinemia: eg.: acute CO poisoning
• •Chronic respiratory failure requiring long term invasive ventilation;
• •Moribund patient
• •Patient under guardianship, deprived of liberties
• •Any other condition, that in the opinion of the IoR/designee, would preclude informed consent (by the spouse/next of kin), make study participation unsafe, complicate interpretation of study outcome data, or otherwise interfere with achieving the study objectives.
• •Low quality index on the SpO2 (Oxygen Saturation Measured by Pulse Oximetry) measurement
• •Patients already enrolled in the present study in a previous episode of acute respiratory failure
• •High PaCO2 - ETCO2 gap (\> 2.6 kPa or 19.5 mmHg) for \> 3 hours
• •Patient tracheostomized at the time of inclusion
• •Patient ventilated with helium