Transurethral Vapor Enucleation Resection of the Prostate (TVERP), Bipolar TURis and HoLEP

Exclusion Criteria

• •1. Patients under anti-inflammatory or steroid therapy
• •2. Patients under anti-coagulation at a level that could be exposed to a very high risk of complications based on a comprehensive pre-operatory evaluation.
• •3. Renal insufficiency Serum creatinine (Scr) \>1.5 x upper limit of normal (ULN); AST and ALT\>2.5 x ULN;Total bilirubin \>1.5 x ULN
• •4. Previous neurogenic lower urinary tract dysfunction.
• •5. Patients with urethral strictures
• •6. Severe pulmonary disease and cardio-vascular disorder 、Coagulopathy，and contraindications to anesthesia and surgery.
• •7. Concurrent participation in any other clinical study
• •8. Any of the following within the 12 months prior to study: myocardial infarction, uncontrolled angina, coronary/peripheral artery bypass graft, symptomatic congestive heart failure, cerebrovascular accident or transient ischemic attack and 6 months for deep vein thrombosis or pulmonary embolism.
• •9. Previous bladder outlet surgery.
• •10. A clinically significant acute illness.
• •11. Intake of medication in which the principle investigator considers to preclude enrollment into the trial.
• •12. Known disease of the central or peripheral nervous system.
• •13. Any clinical evidence of carcinoma of the prostate.
• •14. HIV positive or any other immunosuppressive disorder.
• •15. Psychological/psychiatric disease /Known cognitive disorder.