Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University Hospital Tuebingen
With
Federal Ministry of Health, Germany
Institute of Clinical Epidemiology and applied Biometry, University Tuebingen, Germany
Center of Clinical Trials, University Tuebingen, Germany
University of Ulm
University of Regensburg
University of Wuerzburg
Ludwig-Maximilians - University of Munich
Department of Psychiatry and Psychotherapy, University Leipzig, Germany
Department of Psychiatry, Psychotherapy and Psychosomatics, Medical Faculty, University of Augsburg, Bezirkskrankenhaus Augsburg, Germany
Age
18–70
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
moderate or severe unipolar depression diagnosed according to criteria of Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5)
duration of the current episode must be ≥ 6 weeks and ≤ 2 years
HDRS17 ≥ 18
mild to moderate treatment resistance according to the Antidepressant Treatment History Form \[ATHF-SF\]. Treatment resistance is defined as having failed at least one but no more than three adequate antidepressant treatments in this episode
stable antidepressive medication 4 weeks before treatment or no antidepressive treatment
no further relevant psychiatric axis-I and/or axis-II disorder except for anxiety disorders (according to DSM-5 and SCID-5-PD)
no comorbid psychotic symptoms
ability to give consent
You may not be if
acute suicidality (MADRS item 10 score \> 4)
antiepileptic drugs and/or benzodiazepines corresponding to \> 1mg lorazepam / day
history of brain surgery, significant and clinically relevant brain malformation or neoplasm, head injury, stroke, dementia or other neurodegenerative disorder
history of seizures
previous rTMS treatment
lifetime history of non-response to adequate electroconvulsive therapy (minimum of eight treatments)
deep brain stimulation
cardiac pacemakers, intracranial implant, or metal in the cranium
substance dependence or abuse in the past 3 months (with the exception of tobacco)
severe somatic comorbidity as judged by the study physician
pregnancy
Clareo Health | Treatment of Major Depressive Disorder With Bilateral Theta Burst Stimulation
