Sofosbuvir With Ribavirin or Simeprevir With HCV GT4 Egyptian Patients

Exclusion Criteria

• •coinfected with hepatitis B virus or human immunodeficiency virus infection,
• •any cause of liver disease other than HCV GT4 infection;
• •liver decompensation,
• •hepatocellular carcinoma,
• •major severe illness, such as renal failure, congestive heart failure, thyroid dysfunction, respiratory failure, autoimmune disease and poorly controlled diabetes (HbA1C \>9)
• •Participants with blood picture abnormalities, such as anemia (hemoglobin concentration of 10 g/or less) and thrombocytopenia (platelet count \<50,000 cells/mm3)