Biochemical recurrent and pre-prostatectomy staging participants will be eligible and must meet the following criteria:

1. Age ≥ 18 years

2. Histopathologically confirmed or biopsy proven prostate adenocarcinoma.

3. Concern for metastatic disease in one of the following settings:

1. Initial staging with intermediate to high risk prostate cancer.

2. Biochemical recurrence after initial therapy.

4. Ability to understand a written informed consent document, and the willingness to sign it

Expanded Access 68Gallium-PSMA-11 PET for Prostate Cancer