Excimer Laser Combined With DCB Compared With Angioplasty Alone in the Treatment of Infrapopliteal Lesions.

Exclusion Criteria

• •Patient refusing treatment
• •The target vessel segment diameter is not suitable for available catheter design.
• •Unsuccessfully treated endovascular or bypass( \>30% residual stenosis) proximal ( iliac, superficial femoral, popliteal) inflow limiting arterial/graft stenosis
• •Lesion lies within or adjacent to an aneurysm
• •The patient has a known allergy to heparin, Aspirin or other antiaggregant therapies or a bleeding diatheses or is unable, or unwilling, to tolerate such therapies.
• •The patient has a history of prior life-threatening contrast media reaction.
• •The patient is currently enrolled in another investigational device or drug trial.
• •The patient is currently breast-feeding, pregnant or intends to become pregnant.
• •The patient is unable to provide informed consent
• •The patient has end stage renal disease (currently on any form of dialysis)
• •Known Left Ventricular Ejection Fraction \< 35%
• •The patient has had a myocardial ischemia within 30 days prior to enrollment
• •The patient has had a cardiovascular accident within 90 days prior to enrollment
• •Serum Creatinine \> 150 µmol
• •The patient has a previous bypass in the target limb
• •The patient has a current systemic infection