Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Illinois at Chicago
With
National Institute of Mental Health (NIMH)
Age
25–50
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
25-50 years, as age-related declines in brain connectivity occur starting around 40-45 years of age (49-51);
Participants must meet criteria for one of the following disorders according to Diagnostic and Statistical Manual of Mental Disorders-5 criteria (52): major depressive disorder (MDD), persistent depressive disorder (PDD), bipolar disorder (BD) type I/type II, cyclothymia. To ensure adequate representation across diagnostic categories (including controls), the investigators will cap enrollment of major mood disorders (MDD, BD type I/II) to 50%, PDD and cyclothymia to 25% and recruit a healthy comparison group to comprise the remaining 25% of the sample.
Own a BiAffect-compatible smartphone.
You may not be if
Active suicidal ideation as determined by the Columbia Suicide Severity Rating Scale (C-SSRS)(50), suicide attempt in the last 3 months
Severe cognitive impairment secondary to a neurological disorder (mild cognitive impairment, neurocognitive disorders, traumatic brain injury, developmental delay)
Active moderate or severe alcohol and/or substance use disorders;
Major medical or neurologic illness that would interfere with protocol adherence and/or interpretation of findings; and
Presence of contraindications to MRI.
Pregnancy (positive pregnancy test), trying to become pregnant, or lactation.
