Lead Sponsor

Mansoura University

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Patients are diagnosed as classic TN according to the international headache society classification of headache disorders
•Visual analogue scale (VAS) for pain of at least 4 or more.
•Pain is refractory to medical treatment (for at least 3 months with three drugs including carbamazepine with optimum dosage) or patients who developed intolerable side effects from medications.

•Symptomatic (secondary) TN: which is causes by structural lesion other than neurovascular compression such as multiple sclerosis, tumors, stroke or trauma according to the international headache society classification (IHS, 2013).
•Local infection at the site of the needle puncture. Bleeding tendency or coagulopathy. Previous treatment with invasive treatments such as radiofrequency thermo coagulation, destructive chemical injection, gamma knife treatment, percutaneous balloon micro-compression or microvascular decompression.
•Major mental or psychiatric disorders. History of drug abuse.

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