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Keep this study
Lead
Trinity Health Of New England
The purpose of this prospective interventional study is to gain clinical experience using convalescent plasma transfusion administered to critically ill patients with COVID-19.
1 To study the efficacy of plasma from patients recovered from COVID-19 infection with a high neutralizing antibody titer (NAT) as treatment for individuals who are critically ill with COVID-19.
2\. Determine if the antibodies from convalescent plasma will suppress virus load in critically ill patients with COVID-19.
Age
18–90
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
All genders
Age \> 18 yrs and \< 90 yrs
Must have laboratory confirmed COVID-19
Must provide informed consent
Must have severe or immediately life-threatening COVID-19,
Severe disease is defined as:
dyspnea,
respiratory frequency ≥ 30/min,
blood oxygen saturation ≤ 93%,
partial pressure of arterial oxygen to fraction of inspired oxygen ratio \< 300
lung infiltrates \> 50% within 24 to 48 hours
Life-threatening disease is defined as:
respiratory failure,
septic shock
multiple organ dysfunction or failure
You may not be if
No gender exclusion
Age \< 18 yrs and \> 90 yrs
COVID-19 negative
Clareo Health | Convalescent Plasma in the Treatment of COVID 19