Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Alabama at Birmingham
With
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
University of Texas, Southwestern Medical Center at Dallas
Age
19–75
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Normal Body Mass Index (≥ 18.5 to \< 25); Obese Body Mass Index (≥ 30 to ≤ 45)
Able to provide informed consent
Willingness to consume controlled diet
Composition of most recent stone \> 50% calcium oxalate, no uric acid component
First time or recurrent calcium oxalate stone former
24-hour urine collections with creatinine values within 20% of appropriate ratio of creatinine (mg)/body weight (kg) for gender, and with creatinine values that are consistent between collections (within 20% of each other)
Willingness to stop supplements \[vitamins, Ca (citrate or carbonate) and other minerals, herbal supplements, nutritional aids, probiotics\] for 14 days before start and during study
Willingness to not undertake vigorous exercise during the controlled dietary study
Normal fasting blood Comprehensive Metabolic Panel
Hemoglobin A1c \< 6.5%
No food allergies or intolerance to any of the food in study menus
Permitted/willing to discontinue medications for kidney stone prevention, including thiazides, allopurinol, and febuxostat and citrate preparations, for 14 days before start and during the studies. They will be instructed to restart these medications at the conclusion of the study
