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ACTIVE_NOT_RECRUITINGPHASE2/PHASE3

Somatostatin Analogues With Perioperative Antibiotics Versus Prolonged Antibiotics

Randomized Control Trial Comparing Somatostatin Analogues With Perioperative Antibiotics Versus Prolonged Antibiotics

NCT04329039•Mayo Clinic

Summary

Researchers are trying to determine how the length of antibiotic treatment in addition to octreotide after pancreatic surgery affects the amount of time subjects are hospitalized as well as how many subjects develop pancreatic fistulas.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Patients undergoing a Whipple procedure for various diagnoses (neuroendocrine tumors, adenocarcinoma, benign cystic neoplasms, duodenal and ampullary malignancies, etc) who are deemed intermediate-high risk as per our institutional protocol as shown above.
•Patients \> 18 years of age

Exclusion Criteria

•Negligible and low risk patients
•All patients undergoing arterial resection.
•Age \<18 years
•Currently pregnant

Locations (1)

Mayo Clinic in Rochester

Rochester, Minnesota, United States

Key Dates

Start Date

November 17, 2020

Primary Completion Date

February 7, 2025

Completion Date

December 31, 2026

Last Updated

September 9, 2025

Enrollment

103

ACTUAL participants

Conditions

Pancreatic Diseases

Interventions

Somatostatin analog

DRUG

Effect of Deep Analgosedation vs. Endotracheal Intubation General Anesthesia on on Perioperative Sedation Related Adverse Events in Elderly ERCP Patients

NCT07017283

Biliary and Pancreatic DiseasesEndoscopic Retrograde Cholangiopancreatography (ERCP)

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RECRUITINGPHASE4

Comparison of the Effectiveness of Paracetamol With Ibuprofen or Paracetamol With Metamizole in Treating Pain in Acute Pancreatitis in Children

NCT07024199

Pancreatitis, AcutePain, Acute+5 more

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 9, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Somatostatin Analogues With Perioperative Antibiotics Versus Prolonged Antibiotics

Inclusion Criteria

Exclusion Criteria

Effect of Deep Analgosedation vs. Endotracheal Intubation General Anesthesia on on Perioperative Sedation Related Adverse Events in Elderly ERCP Patients

Comparison of the Effectiveness of Paracetamol With Ibuprofen or Paracetamol With Metamizole in Treating Pain in Acute Pancreatitis in Children

Validation of an AI-Assisted Pancreatic EUS System for Training Improvement: a Prospective, Multi-Center, Randomized Trial

Patient Reported Experience in Endoscopic Ultrasound

Endoscopic Management of Biliopancreatic Disease in the Lombardy Pancreas Units

The 22G Trident Needle Combined With Different Aspiration Techniques for Endoscopic Ultrasound-guided Fine-needle Biopsy