Nebulized MgSO4 in Persistent Pulmonary Hypertension of Newborn

Exclusion Criteria

• •1. failure to obtain informed consent.
• •2. infants of mothers who received magnesium sulfate within 48 hours before labor.
• •3. congenital heart diseases (other than PDA and foramen ovale).
• •4. major congenital anomalies (including congenital diaphragmatic hernia and lung hypoplasia).
• •5. prior need for cardiopulmonary resuscitation.
• •6. mean arterial blood pressure (MABP) \< 35 mmHg despite therapy with volume infusions and inotrpic support.
• •7. impaired kidney function.
• •8. prior administration of pulmonary vasodilators.